Early Interventions for Common Mental Disorders in High-Risk Populations Through Transdiagnostic Trait-Focused Web-Based Interventions

WP leaders Ulrike Schmidt, Peter Musiat (KCL)

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The overall objective of this work package is to investigate the ability of transdiagnostic trait-focused web-based interventions to prevent or ameliorate severity of symptoms of common mental disorders (CMHDs) in young people at high risk (based on their personality traits, e.g. high perfection or trait anxiety) and carers of people with anorexia nervosa (AN), who are at high risk of CMHDs both because of their personality traits and by virtue of caring for someone with a severe mental illness. Two randomized controlled trials (RCTs) will be conducted with the aim of investigating the effectiveness, acceptability, costs and cost-effectiveness of a transdiagnostic trait-focused web-based intervention for young people at high risk of CMHD compared to an active control intervention (information on housing, finance and study) and a guided transdiagnostic web-based intervention for CMHDs in carers of people with AN compared to an unguided web-based intervention. This RCT will also investigate the impact of the intervention on the person with AN.

Specific objectives are:

  • To provide transdiagnostic trait-focused web-based interventions (PLUS and We Can) for the prevention of CMHDs to university students at high risk for developing such disorders, as well as to carers of sufferers from AN
  • To investigate the effectiveness of PLUS and We Can with regard to preventing or ameliorating severity of symptoms of CMHDs in high-risk populations in three countries (UK, Germany, Austria)
  • To analyze feasible strategies to implement PLUS and We Can and to identify possible implementation barriers from users, services and stakeholders